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老年人的雷诺现象:诊断考量与管理

Raynaud's phenomenon in older adults: diagnostic considerations and management.

作者信息

Ling S M, Wigley F M

机构信息

Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

Drugs Aging. 1999 Sep;15(3):183-95. doi: 10.2165/00002512-199915030-00002.

Abstract

Raynaud's phenomenon (RP) is characterised by sensitivity to cold temperatures associated with either biphasic or uniphasic change in colour of the digits. Since few studies are available which include older adults, the prevalence of RP in the older adult population is estimated from surveys or studies of the general population. The causes of RP in older adults may differ significantly from those in young adults and, therefore, so would the evaluation of RP. Because of comorbitis that accompany advancing age, the management of RP in older adult patients must take into consideration toxicity and adverse reactions that may develop, especially in the frail individual. Although nonpharmacological therapy is preferable, slow-release calcium antagonists provide a relatively well tolerated and effective treatment for moderate to severe RP in older adult patients. Aggressive treatment including hospitalisation is appropriate for older adult patients during periods of critical digital ischaemia associated with RP.

摘要

雷诺现象(RP)的特征是对低温敏感,伴有手指颜色的双相或单相变化。由于针对老年人的研究较少,因此老年人中RP的患病率是通过对普通人群的调查或研究来估计的。老年人RP的病因可能与年轻人有显著差异,因此,对RP的评估也会有所不同。由于随着年龄增长会出现合并症,老年患者中RP的管理必须考虑到可能发生的毒性和不良反应,尤其是在身体虚弱的个体中。尽管非药物治疗更为可取,但缓释钙拮抗剂为老年患者中、重度RP提供了耐受性相对良好且有效的治疗方法。在与RP相关的严重手指缺血期,包括住院治疗在内的积极治疗对老年患者是合适的。

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