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非球面角膜表面与基质内角膜环片的特征分析

Characterization of the aspheric corneal surface with intrastromal corneal ring segments.

作者信息

Holmes-Higgin D K, Baker P C, Burris T E, Silvestrini T A

机构信息

Northwest Corneal Services and the Corneal Topography Research Center, Portland, Oregon 97223, USA.

出版信息

J Refract Surg. 1999 Sep-Oct;15(5):520-8. doi: 10.3928/1081-597X-19990901-04.

Abstract

PURPOSE

Anterior corneal surface asphericity was examined in eyes of Phase II clinical trial participants, before and after intrastromal corneal ring segments (ICRS, Intacs) refractive surgery, and surveyed for relationship to clinical visual performance.

METHODS

Aspheric test objects with surface asphericity (Q) ranging from -0.01 Q to -1.44 Q and base radius of curvatures ranging from 7.5 mm to 9.0 mm were measured topographically using videokeratography. Radius of curvature asphericity profile plots were produced for test objects and compared to similar plots created for trial participant eyes (n=25) to quantify corneal asphericity. The potential effects of different amounts of corneal asphericity were assessed using measurement of uncorrected and spectacle-corrected visual acuity and photopic contrast sensitivity.

RESULTS

Preoperative corneal asphericity ranged from -0.01 Q to -0.81 Q and postoperative from -0.01 Q to -1.44 Q. Preoperative uncorrected visual acuity was significantly related to corneal asphericity; more myopic eyes tended to have more prolate corneal asphericity. Corneal asphericity was not significantly related to spectacle-corrected visual acuity or photopic contrast sensitivity, before or after surgery.

CONCLUSION

Postoperative corneal asphericity values demonstrated that intrastromal corneal ring segments (Intacs) produced a prolate aspheric surface for myopic correction from -1.00 D to -6.00 D. This study indicated that the range of corneal asphericity measured in these 25 eyes, before and after surgery, provided good visual acuity and normal contrast sensitivity.

摘要

目的

在基质内角膜环片(ICRS,Intacs)屈光手术前后,对II期临床试验参与者的眼睛进行角膜前表面非球面性检查,并调查其与临床视觉表现的关系。

方法

使用角膜地形图仪测量表面非球面性(Q)范围为-0.01 Q至-1.44 Q且曲率半径范围为7.5 mm至9.0 mm的非球面测试物体。为测试物体制作曲率半径非球面轮廓图,并与为试验参与者眼睛(n = 25)创建的类似图进行比较,以量化角膜非球面性。通过测量未矫正和眼镜矫正视力以及明视觉对比敏感度来评估不同量角膜非球面性的潜在影响。

结果

术前角膜非球面性范围为-0.01 Q至-0.81 Q,术后为-0.01 Q至-1.44 Q。术前未矫正视力与角膜非球面性显著相关;近视程度越高的眼睛往往具有更椭圆的角膜非球面性。手术前后,角膜非球面性与眼镜矫正视力或明视觉对比敏感度均无显著相关性。

结论

术后角膜非球面性值表明,基质内角膜环片(Intacs)为-1.00 D至-6.00 D的近视矫正产生了一个椭圆非球面表面。本研究表明,在这25只眼睛手术前后测量的角膜非球面性范围提供了良好的视力和正常的对比敏感度。

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