Ohba Y, Suzuki H, Hiraga H, Ito T, Sawa H, Nagai M, Satoh S I, Iwaki H, Nagashima K
Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine, Sapporo, Japan.
Pathol Int. 1999 Jul;49(7):653-7. doi: 10.1046/j.1440-1827.1999.00916.x.
Peritoneal sarcomatosis was found in a 53-year-old male who had a history of resection of clear cell sarcoma (CCS) of the right wrist 7 years previously. Both the previous wrist tumor and the peritoneal disseminants consisted of small, spindle-shaped cells occasionally containing melanophages. Histologic features, histochemical demonstration of argentaffin granules, immunohistochemical reaction with HMB 45, and the demonstration of a chimeric transcript of EWS-ATF-1 established the diagnosis of CCS in the peritoneal tumors. As far as we are aware, this is the first case of a peritoneal sarcomatosis associated with CCS.
在一名53岁男性中发现了腹膜肉瘤病，该患者7年前有右腕部透明细胞肉瘤（CCS）切除史。先前的腕部肿瘤和腹膜播散灶均由偶尔含有噬黑素细胞的小梭形细胞组成。组织学特征、嗜银颗粒的组织化学显示、与HMB 45的免疫组化反应以及EWS-ATF-1嵌合转录本的显示确立了腹膜肿瘤中CCS的诊断。据我们所知，这是首例与CCS相关的腹膜肉瘤病病例。
