Rowe-Magnus D A, Mazel D
Unité de Programmation Moléculaire et Toxicologie Genétique (UPMTG) Centre National de Recherche Scientifique (CNRS) URA 1444 Département des Biotechnologies Institut Pasteur 25 rue du Dr Roux, 75724, Paris, France.
Curr Opin Microbiol. 1999 Oct;2(5):483-8. doi: 10.1016/s1369-5274(99)00004-1.
Integrons are the primary mechanism for antibiotic-resistance gene capture and dissemination among Gram-negative bacteria. The recent finding of super-integron structures in the genomes of several bacterial species has expanded their role in genome evolution and suggests that they are the source of mobile multi-resistant integrons.
整合子是革兰氏阴性菌中抗生素抗性基因捕获和传播的主要机制。最近在几种细菌物种的基因组中发现了超级整合子结构，这扩展了它们在基因组进化中的作用，并表明它们是可移动多抗性整合子的来源。
