Siggelkow S, Kossev A, Schubert M, Kappels H H, Wolf W, Dengler R
Department of Neurology, Medical School Hannover, D-30623 Hannover, Germany.
Muscle Nerve. 1999 Nov;22(11):1544-8. doi: 10.1002/(sici)1097-4598(199911)22:11<1544::aid-mus9>3.0.co;2-8.
Augmentation of motor evoked potentials (MEPs) by muscle vibration (MV) was studied in 10 healthy subjects with regard to the vibration frequency (VF). The extensor carpi radialis muscle (ECR) was vibrated using VFs of 80, 120, and 160 Hz. Motor evoked potentials following transcranial magnetic stimulation were recorded simultaneously from the vibrated ECR and the antagonist flexor carpi radialis muscle (FCR) without MV, 0.5 s and 3 s after onset of MV and 1 s after offset. Only the VFs of 80 Hz and 120 Hz caused MEP augmentation and latency shortening in ECR, whereas depression of MEPs in FCR was induced by all VFs used. It appears that MEP augmentation and latency shortening in ECR are mediated by the primary muscle spindle endings which respond with optimal discharge rates to VFs of up to 100 Hz. Motor evoked potential depression in FCR, being well expressed also with VF 160 Hz, seems to involve other dynamic mechanoreceptors.
在10名健康受试者中，研究了肌肉振动（MV）对运动诱发电位（MEP）的增强作用，并探讨了振动频率（VF）的影响。使用80、120和160Hz的振动频率对桡侧腕伸肌（ECR）进行振动。在无MV时、MV开始后0.5秒和3秒以及MV停止后1秒，同时记录经颅磁刺激后振动的ECR和拮抗肌桡侧腕屈肌（FCR）的运动诱发电位。只有80Hz和120Hz的振动频率可导致ECR的MEP增强和潜伏期缩短，而所有使用的振动频率均会引起FCR的MEP抑制。似乎ECR的MEP增强和潜伏期缩短是由初级肌梭末梢介导的，这些末梢对高达100Hz的振动频率以最佳放电率做出反应。FCR中的运动诱发电位抑制在160Hz的振动频率下也表现明显，似乎涉及其他动态机械感受器。
