Binder Christian, Kaya Ali Ekber, Liepert Joachim
Department of Neurorehabilitation, Kliniken Schmieder, Zum Tafelholz 8, D-78476 Allensbach, Germany.
Muscle Nerve. 2009 Jun;39(6):776-80. doi: 10.1002/mus.21240.
We tested whether the silent period, an indicator of inhibitory neuronal activity, is modulated by muscle vibration. Vibration was applied to the right extensor carpi radialis (ECR) muscle in 17 healthy subjects and, as a control experiment, to the dorsal terminal phalanges in 5 subjects. Data before vibration were compared with those during vibration. The cortical silent period (CSP) was evoked by transcranial magnetic stimuli (TMS) during voluntary wrist flexion or during voluntary wrist extension. TMS-evoked motor potentials (MEPs) of the flexor carpi radialis (FCR) muscle were recorded during muscle relaxation. The mixed nerve silent period (MNSP) was obtained by electrical stimulation of the median nerve during wrist flexion. ECR vibration induced a significant prolongation of the CSP in FCR. CSP increases induced by vibration of the dorsal terminal phalanges were significantly less pronounced. In ECR, the CSP tended to be shortened. MEPs and MNSP remained unchanged. We conclude that vibration enhances inhibitory neuronal properties in a non-vibrated antagonistic muscle, presumably at a supraspinal level. These results may be relevant for the treatment of spasticity of the upper extremity.
我们测试了作为抑制性神经元活动指标的静息期是否会受到肌肉振动的调节。对17名健康受试者的右侧桡侧腕伸肌（ECR）施加振动，并作为对照实验，对5名受试者的手指末节背侧施加振动。将振动前的数据与振动期间的数据进行比较。在自愿腕部屈曲或自愿腕部伸展期间，通过经颅磁刺激（TMS）诱发皮质静息期（CSP）。在肌肉放松期间记录桡侧腕屈肌（FCR）的TMS诱发运动电位（MEP）。通过在腕部屈曲期间电刺激正中神经获得混合神经静息期（MNSP）。ECR振动导致FCR的CSP显著延长。手指末节背侧振动引起的CSP增加明显不那么显著。在ECR中，CSP有缩短的趋势。MEP和MNSP保持不变。我们得出结论，振动增强了未振动的拮抗肌中的抑制性神经元特性，推测是在脊髓上水平。这些结果可能与上肢痉挛的治疗有关。
