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在任何患有梗阻性黄疸的患者的鉴别诊断中,必须排除Mirizzi综合征。

Mirizzi's syndrome must be ruled out in the differential diagnosis of any patients with obstructive jaundice.

作者信息

Karakoyunlar O, Sivrel E, Koc O, Denecli A G

机构信息

SSK Izmir Teaching Hospital, Department of 1st General Surgery, Turkey.

出版信息

Hepatogastroenterology. 1999 Jul-Aug;46(28):2178-82.

Abstract

BACKGROUND/AIMS: Mirizzi syndrome is a rare benign complication of long-standing cholelithiasis and neither diagnostic modality nor clinical feature has a 100% sensitivity and specificity. The objective of our study was to call attention to the importance of this rare syndrome with its miscellaneous treatments.

METHODOLOGY

Between January 1992 and June 1997, a total of 8 (4 females and 4 males) patients, who were operated and diagnosed as Mirizzi syndrome, were retrospectively evaluated.

RESULTS

The mean age was 53.75 years. During the same time period 0.98% of the total 812 cholelithiasis patients were Mirizzi syndrome. The ultrasound was used in 7, computed tomography (CT) in 4 and endoscopic retrograde cholangiopancreatography (ERCP) in 2 cases. Ultrasound allowed the detection of cholelithiasis in all, but proximal bile duct dilatation in only 71% of cases. CT detected the non-specific findings of syndrome in 75% of cases. In 2 patients, because of the difficulties due to the patients themselves and the technical management problems. ERCP could not detect the pathology properly. In 2 of 5 type I patients, we performed only cholecystectomy and in another 2 cholecystectomy plus T-tube drainage. In 1 case, due to major hepatic duct injury during surgery, cholecystectomy plus hepaticojejunostomy over the Y-stent was performed. Biliary fistula developed in 1 patient with T-tube drainage and was successfully managed with conservative treatment. In all type II patients we preferred cholecystectomy plus choledochoduodenostomy and all of them were free of complications.

CONCLUSIONS

If there is no question about the security of the common bile duct at surgery in type I patients, we recommended cholecystectomy, otherwise cholecystectomy plus exploration of common bile duct and/or drainage should be the procedure of choice. However, in type II patients cholecystectomy plus choledochoduodenostomy is a safe and effective procedure to perform.

摘要

背景/目的:Mirizzi综合征是长期胆结石的一种罕见良性并发症,无论是诊断方法还是临床特征都没有100%的敏感性和特异性。我们研究的目的是通过其多种治疗方法来引起对这种罕见综合征重要性的关注。

方法

回顾性评估1992年1月至1997年6月期间共8例(4例女性和4例男性)接受手术并诊断为Mirizzi综合征的患者。

结果

平均年龄为53.75岁。在同一时期,812例胆结石患者中0.98%为Mirizzi综合征。7例患者使用了超声检查,4例使用了计算机断层扫描(CT),2例使用了内镜逆行胰胆管造影(ERCP)。超声检查能发现所有患者的胆结石,但仅71%的病例能检测到近端胆管扩张。CT在75%的病例中检测到综合征的非特异性表现。2例患者由于患者自身原因及技术管理问题,ERCP未能正确检测出病变。5例I型患者中的2例仅进行了胆囊切除术,另外2例进行了胆囊切除术加T管引流。1例患者在手术中因肝总管严重损伤,进行了胆囊切除术加Y型支架上的肝管空肠吻合术。1例T管引流患者发生胆瘘,经保守治疗成功处理。所有II型患者均首选胆囊切除术加胆总管十二指肠吻合术,且均无并发症。

结论

对于I型患者,如果手术中胆总管安全没有问题,我们建议行胆囊切除术,否则胆囊切除术加胆总管探查和/或引流应作为首选手术方式。然而,对于II型患者,胆囊切除术加胆总管十二指肠吻合术是一种安全有效的手术方式。

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