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经颈静脉肝内门体分流术的功能能否通过多普勒超声进行无创评估?

[Can the function of the transjugular intrahepatic portosystemic shunt be evaluated noninvasively by Doppler sonography?].

作者信息

Ullerich H, Menzel J, Kucharzik T, Reimer P, Vestring T, Domschke W

机构信息

Medizinische Klinik und Poliklinik B, Westfälischen Wilhelms-Universität, Münster.

出版信息

Z Gastroenterol. 1999 Sep;37(9):771-8.

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment of complications due to portal hypertension. Possible shunt stenosis or shunt occlusion make periodical assessment of stent function necessary. Direct portal venography is the gold standard in morphologic and functional surveillance of TIPS. Controversially discussed is whether Doppler ultrasonography is effective in hemodynamical evaluation of TIPS and sufficient in prediction of shunt dysfunction. In 39 patients, 147 Doppler ultrasonographical examinations were performed and correlated with the results obtained by direct portal venography in TIPS follow-up, 43 of 47 hemodynamically relevant stenoses, including six shunt occlusions, were being diagnosed correctly by Doppler ultrasonography, by assessing maximal flow velocity in portal vein proximal to the TIPS (sensitivity 91.5%; specificity 97%). If Doppler ultrasonographical measurement of maximal flow velocity was performed within the proximal stent itself, sensitivity was only 70.4% and specificity 27%. In conclusion, assessment of portal maximal flow velocity more accurately represents hemodynamical TIPS function than Doppler ultrasonographical measurement within the proximal stent tract itself. Since, according to data presented. Doppler ultrasonography appears to be able to detect hemodynamically significant TIPS stenoses, it might reduce the number of invasive angiographies and thus contribute to more cost-effective follow-up of TIPS patients.

摘要

经颈静脉肝内门体分流术(TIPS)是治疗门静脉高压并发症的一种有效方法。可能出现的分流狭窄或分流闭塞使得定期评估支架功能成为必要。直接门静脉造影是TIPS形态学和功能监测的金标准。关于多普勒超声检查在TIPS血流动力学评估中是否有效以及在预测分流功能障碍方面是否充分,存在争议。对39例患者进行了147次多普勒超声检查,并将其与TIPS随访中直接门静脉造影的结果进行关联。在47例血流动力学相关狭窄(包括6例分流闭塞)中,有43例通过多普勒超声检查正确诊断,通过评估TIPS近端门静脉的最大流速(敏感性91.5%;特异性97%)。如果在近端支架本身内进行多普勒超声最大流速测量,敏感性仅为70.4%,特异性为27%。总之,与在近端支架管腔内进行多普勒超声测量相比,评估门静脉最大流速能更准确地反映TIPS的血流动力学功能。根据所提供的数据,由于多普勒超声似乎能够检测出血流动力学上显著的TIPS狭窄,它可能会减少侵入性血管造影的次数,从而有助于更具成本效益地对TIPS患者进行随访。

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