Jablonska S, Blaszczyk M
Department of Dermatology, Warsaw School of Medicine, Koszykowa 82a, 02-008 Warsaw, Poland.
Eur J Dermatol. 1999 Oct-Nov;9(7):551-4.
We present four cases of scleromyxedema with scleroderma-like cutaneous changes mimicking systemic sclerosis and stress the importance of their differentiation from true scleroderma. Scleromyxedema should be recognized as an entity since it differs from scleroderma in the pathogenesis, histopathology of cutaneous lesions, type of visceral involvement (if present), frequent association with paraproteinemia, the course and prognosis.
我们报告了4例硬肿病样皮肤改变的硬化性黏液水肿病例，这些改变酷似系统性硬化症，并强调了将其与真性硬皮病区分开来的重要性。硬化性黏液水肿应被视为一种独立的疾病，因为它在发病机制、皮肤病变的组织病理学、内脏受累类型（如果存在）、与副蛋白血症的频繁关联、病程及预后等方面与硬皮病不同。
