Brenner R R
Acta Physiol Lat Am. 1976;26(6):453-62.
The research of essential fatty acids biochemistry in Argentina was initiated approximately twenty years ago. These investigations together with the outstanding findings obtained in other countries proved the existence of different types of reactions. The essential fatty acids, linolenic and alpha linolenic, are converted by desaturation and elongation reactions in higher homologs building families of fatty acids. These reactions are regulated by dietary components, hormones, temperature and products of reaction. Retroconversion reactions transform the higher homologs, especially of 22 carbons back again to lower homologs avoiding beta oxidation. They are incorporated in the lipids to build the lipoproteic membranes increasing their fluidity. Specific acids are converted to prostaglandins that function as specific hormones.
阿根廷对必需脂肪酸生物化学的研究大约始于二十年前。这些研究以及在其他国家取得的显著发现证明了不同类型反应的存在。必需脂肪酸，即亚油酸和α-亚麻酸，通过去饱和和延长反应转化为更高同系物，从而构建脂肪酸家族。这些反应受饮食成分、激素、温度和反应产物的调节。逆向转化反应将更高同系物，尤其是22碳的同系物再次转化为更低同系物，以避免β氧化。它们被整合到脂质中以构建脂蛋白膜，从而增加其流动性。特定的酸会转化为发挥特定激素功能的前列腺素。
