Hannah W N, Ender P T
Department of Internal Medicine, Wright-Patterson Air Force Base Medical Center, Wright-Patterson Air Force Base, Ohio 45433, USA.
Clin Infect Dis. 1999 Sep;29(3):659-61. doi: 10.1086/598647.
In recent years manufacturers have developed several products containing saprophytic bacteria, previously believed to be of minimal pathogenicity. We describe the first case of persistent Bacillus licheniformis bacteremia occurring after intentional injection of a consumer product that includes B. licheniformis spores. We postulate that these spores remained in the tissue, unaffected by antimicrobials, ultimately necessitating soft-tissue debridement of the area surrounding the injection site. On the basis of this case and a review of the literature, we submit that some consumer products contain bacteria with demonstrated pathogenicity. Manufacturers should study these bacteria in detail in order to rapidly provide information such as bacteriologic data and antimicrobial susceptibility data to clinicians.
近年来，制造商开发了几种含有腐生菌的产品，以前认为这些腐生菌致病性极小。我们描述了首例因故意注射一种含有地衣芽孢杆菌孢子的消费品后发生的持续性地衣芽孢杆菌菌血症病例。我们推测这些孢子残留在组织中，不受抗菌药物影响，最终需要对注射部位周围区域进行软组织清创术。基于该病例及文献回顾，我们认为一些消费品含有已证实具有致病性的细菌。制造商应详细研究这些细菌，以便迅速向临床医生提供诸如细菌学数据和抗菌药敏数据等信息。
