Jensen R E, Johnson A E
Department of Cell Biology and Anatomy, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Curr Biol. 1999 Oct 21;9(20):R779-82. doi: 10.1016/S0960-9822(00)80012-3.
Hsp70 proteins in the lumen of the endoplasmic reticulum and in the mitochondrial matrix are thought to drive the translocation of proteins into each organelle. Recent experiments aimed at distinguishing between two models for Hsp70 function appear to reach opposite conclusions.
内质网腔和线粒体基质中的热休克蛋白70(Hsp70)被认为可驱动蛋白质转运至各细胞器中。近期旨在区分Hsp70功能的两种模型的实验似乎得出了相反的结论。