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小儿短肠综合征的发病率及死亡率分析

An analysis of the morbidity and mortality of short-bowel syndrome in the pediatric age group.

作者信息

Coran A G, Spivak D, Teitelbaum D H

机构信息

Section of Pediatric Surgery, University of Michigan, Medical School, Ann Arbor 48109-0245, USA.

出版信息

Eur J Pediatr Surg. 1999 Aug;9(4):228-30. doi: 10.1055/s-2008-1072250.

DOI:10.1055/s-2008-1072250
PMID:10532263
Abstract

Twenty-two children with short-bowel syndrome (SBS) were treated at the C. S. Mott Children's Hospital in the University of Michigan Medical Center between June 1983 and May 1993. Definition of SBS was loss of 70% or more of the total small bowel. Seventeen of these children are currently alive, a 77% survival rate. Patients were followed for a mean of 1,148 days. The mean age of SBS development was 71 days of life. The only predictive indicator of patient survival was direct bilirubin levels. Sixty-seven percent of the children died if they had a direct bilirubin of > 4 mg/dl > or = 6 months duration.

摘要

1983年6月至1993年5月期间,密歇根大学医学中心的C.S. 莫特儿童医院对22名短肠综合征(SBS)患儿进行了治疗。SBS的定义为小肠总长度丧失70%或更多。这些患儿中有17名目前仍然存活,生存率为77%。对患者进行了平均1148天的随访。SBS发病的平均年龄为出生后71天。患者生存的唯一预测指标是直接胆红素水平。如果直接胆红素>4mg/dl且持续时间≥6个月,67%的患儿会死亡。

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