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C57BL/6J、DBA/2J和B6D2F1小鼠的行为特征,这些特征可能对老年学研究有用。

Behavioral characteristics of C57BL/6J. DBA/2J, and B6D2F1 mice which are potentially useful for gerontological research.

作者信息

Sprott R L

出版信息

Exp Aging Res. 1975 Nov;1(2):313-23. doi: 10.1080/03610737508257969.

DOI:10.1080/03610737508257969
PMID:1053265
Abstract

This review summarizes the behavioral characteristics of C57BL/6J, DBA/2J, and B6D2F1, hybrid mice which are most likely to be of interest to gerontological scientists. Where possible, the characteristics of young and old mice are included. Where no information exists about the behavior of older mice of these genotypes, but there is reason to believe that information about mice might be useful for aging research, this information is included. The purpose of the review is to acquaint gerontologists with the availability of genetically defined animal models for aging research, to present what is known about these models, and to suggest areas of research which could profit from more attention.

摘要

本综述总结了C57BL/6J、DBA/2J和B6D2F1杂交小鼠的行为特征,这些特征很可能是老年学科学家感兴趣的。在可能的情况下,纳入了年轻和年老小鼠的特征。对于这些基因型的老年小鼠的行为尚无相关信息,但有理由相信有关小鼠的信息可能对衰老研究有用,因此也纳入了这些信息。本综述的目的是让老年学家了解用于衰老研究的基因定义动物模型的可用性,介绍关于这些模型的已知信息,并提出可能因更多关注而受益的研究领域。

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