Maiques-Montesinos V, Cervera-Sanchez J, Bellver-Pradas J, Abad-Carrascosa A, Serra-Serra V
Hospital Maternal La Fé, Valencia, Spain.
Acta Obstet Gynecol Scand. 1999 Oct;78(9):789-92.
The present work is an audit of post-cesarean section morbidity in HIV-positive women in the tertiary teaching hospital La Fé, Valencia, Spain.
Retrospective case-control study.
Forty-five HIV-positive pregnant women and 90 appropriately matched controls, delivered by cesarean section in the same hospital and managed using a uniform protocol.
The duration of stay in hospital after cesarean section, the need for postoperative antibiotics and the incidence of major and minor puerperal complications. Baseline characteristics of HIV-positive women were also analyzed in relation to the morbidity after surgery.
Chi-square analysis for categorical data and parametric and non-parametric tests for numerical data, where appropriate.
Most HIV-positive women (86.7%) had a complicated recovery after surgery. A longer duration of stay in hospital (p<0.0005) and a greater incidence of major (p<0.003) and minor (p<0.00001) postoperative complications were observed in the HIV-positive group compared to the control group. HIV-positive women with > or =500 CD4 lymphocytes/mm3 had less post-cesarean section morbidity
A greater post-cesarean section morbidity was found in HIV-positive women compared to the control women. Immunological status of HIV-positive women may be important in predicting puerperal morbidity after surgery.
本研究是对西班牙巴伦西亚拉费三级教学医院中HIV阳性女性剖宫产术后发病率的一项审计。
回顾性病例对照研究。
45名HIV阳性孕妇和90名匹配得当的对照者，均在同一家医院接受剖宫产，并采用统一方案进行管理。
剖宫产术后住院时间、术后使用抗生素的必要性以及产后主要和次要并发症的发生率。还分析了HIV阳性女性的基线特征与术后发病率的关系。
对分类数据采用卡方分析，对数值数据在适当情况下采用参数检验和非参数检验。
大多数HIV阳性女性（86.7%）术后恢复情况复杂。与对照组相比，HIV阳性组的住院时间更长（p<0.0005），术后主要并发症（p<0.003）和次要并发症（p<0.00001）的发生率更高。CD4淋巴细胞计数≥500/mm³的HIV阳性女性剖宫产术后发病率较低。
与对照女性相比，HIV阳性女性剖宫产术后发病率更高。HIV阳性女性的免疫状态可能对预测术后产褥期发病率很重要。
