Bauersfeld U, Nowak B, Molinari L, Malm T, Kampmann C, Schönbeck M H, Schüller H
Division of Pediatric Cardiology, Children's University Hospital, Zurich, Switzerland.
Ann Thorac Surg. 1999 Oct;68(4):1380-3. doi: 10.1016/s0003-4975(99)00695-5.
Permanent cardiac pacing in children results commonly in augmented energy consumption because of the high pacing rates and the ample stimulation safety margin applied in children. Cardiovascular anatomy and limited venous access sometimes preclude the otherwise preferred endocardial approach. In this multicenter patient series, we studied the feasibility, safety, and energy saving obtained by a combination of steroid-eluting epicardial leads with autocapture devices capable of ongoing adjustment of the stimulation output to the prevailing threshold.
Autocapture devices (Pacesetter Microny SR+/- and Regency SR+/-; Pacesetter, Solna, Sweden) and steroid-eluting epicardial pacing leads (Medtronic CapSure Epi 10366; Medtronic, Inc, Minneapolis, MN) were implanted in 14 children. Thresholds, telemetry data, evoked response, and polarization signals were obtained at discharge and follow-up, and battery service life was calculated.
During a median follow-up of 6.5 months, autocapture pacing was applied in 12 of 14 children. The automatically adjusted pulse amplitude of autocapture devices demonstrated low-energy pacing with no significant changes between discharge and 6 months follow-up (1.1 +/- 0.3 versus 0.9 +/- 0.3 V). Autocapture-programmed pacemakers had calculated life spans of 7.8 +/- 1.4 years (Microny) and 21.0 +/- 1.6 years (Regency). No adverse effects were noted.
Autocapture-controlled pacing with bipolar epicardial pacing leads is feasible and safe in children. Autocapture programming results in substantial energy savings and extends battery life markedly.
由于儿童起搏频率高且应用了充足的刺激安全裕度,永久性心脏起搏通常会导致能量消耗增加。心血管解剖结构和有限的静脉通路有时会使原本更可取的心内膜途径无法实施。在这个多中心患者系列中,我们研究了将类固醇洗脱型心外膜导线与能够根据当前阈值持续调整刺激输出的自动夺获装置相结合所获得的可行性、安全性和节能效果。
将自动夺获装置(Pacesetter Microny SR+/-和Regency SR+/-;瑞典索尔纳的Pacesetter公司)和类固醇洗脱型心外膜起搏导线(美敦力CapSure Epi 10366;明尼阿波利斯的美敦力公司)植入14名儿童体内。在出院时和随访时获取阈值、遥测数据、诱发反应和极化信号,并计算电池使用寿命。
在中位随访6.5个月期间,14名儿童中有12名应用了自动夺获起搏。自动夺获装置自动调整的脉冲幅度显示为低能量起搏,出院时和随访6个月之间无显著变化(1.1±0.3伏对0.9±0.3伏)。自动夺获程控起搏器的计算寿命为7.8±1.4年(Microny)和21.0±1.6年(Regency)。未观察到不良反应。
在儿童中,使用双极心外膜起搏导线进行自动夺获控制的起搏是可行且安全的。自动夺获程控可显著节省能量并明显延长电池寿命。