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[糖尿病孕妇的围产期发病率和死亡率]

[Perinatal morbidity and mortality in pregnant women with diabetes mellitus].

作者信息

Sandoval T, Jiménez G, Uribe S, Partida-Hernández G, González S, Arreola F

机构信息

Departamento de Medicina Interna, HGO-LCA, IMSS, México, D.F.

出版信息

Ginecol Obstet Mex. 1995 May;63:181-5.

PMID:7789845
Abstract

The purpose of this study was to investigate the perinatal morbidity and mortality in all the diabetic pregnancies seen at the HGO-"LCA" from January 1992 to December 1993. In that period 186 women (mean age 31 yr) were diagnosed as having diabetes during pregnancy: 54% of them had DMG, 40% DM-II and 6% DM-I, with serum glucose concentration of 133 +/- 41 mg/dL. Neonatal morbidity was given by macrosomia (17%), prematurity (14%), hyperbilirubinemia (11%), hypoglycemia (8%), congenital malformation (6%) and hypocalcemia (4%). Perinatal mortality was 5.3%. The principal causes of maternal morbidity were preeclampsia (17%), polyhydramnios (16%), pyelonephritis (4%) and ketoacidosis (0.05%). Cesarean section was performed in 62% of all diabetic patients. There was not any maternal death. This results showed a high perinatal morbidity-mortality in pregnancies complicated by diabetes mellitus which reclaim a better metabolic control during gestation period.

摘要

本研究的目的是调查1992年1月至1993年12月在HGO - “LCA”所见的所有糖尿病妊娠的围产期发病率和死亡率。在此期间,186名女性(平均年龄31岁)在孕期被诊断患有糖尿病:其中54%为妊娠期糖尿病(DMG),40%为2型糖尿病(DM-II),6%为1型糖尿病(DM-I),血清葡萄糖浓度为133±41mg/dL。新生儿发病率表现为巨大儿(17%)、早产(14%)、高胆红素血症(11%)、低血糖(8%)、先天性畸形(6%)和低钙血症(4%)。围产期死亡率为5.3%。孕产妇发病的主要原因是先兆子痫(17%)、羊水过多(16%)、肾盂肾炎(4%)和酮症酸中毒(0.05%)。62%的糖尿病患者进行了剖宫产。无孕产妇死亡。这些结果表明,糖尿病合并妊娠的围产期发病率和死亡率较高,这要求在妊娠期进行更好的代谢控制。

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