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科威特孕妇中人类细小病毒B19抗体的流行情况。

The prevalence of antibody to human parvovirus B19 in pregnant women in Kuwait.

作者信息

Maksheed M, Pacsa A S, Essa S S, Ahmed M A, Monem R A, Surkouh M

机构信息

Department of Obstetrics and Gynaeology, Faculty of Medicine, Kuwait University, Safat.

出版信息

Acta Trop. 1999 Oct 15;73(3):225-9. doi: 10.1016/s0001-706x(99)00033-9.

Abstract

Infection with parvovirus B19 during pregnancy is known to be associated with various fetal damage, such as aplastic anemia and hydrops fetalis. Our objective was to study the seroprevalence of parvovirus B19 in the obstetric population in Kuwait and to compare this with that in the adult population in other regions. Blood samples from 1047 pregnant women were used in this prospective study. Information regarding patient's age, parity, nationality and symptoms was obtained at the time of collection of the sample. Blood was tested for IgG and IgM antibodies specific for parvovirus B19 using the ELISA technique. The overall prevalence for IgG and IgM was 53.3 and 2.2%, respectively. IgG seropositivity was higher in non-Kuwaiti women, while IgM antibodies was more frequent in Kuwaiti women. A total of 17.4% of the acutely infected patients were symptomatic. Prevalence of parvovirus B19 infection in Kuwait is comparable with that in the other countries.

摘要

已知孕期感染细小病毒B19与各种胎儿损伤有关,如再生障碍性贫血和胎儿水肿。我们的目的是研究科威特产科人群中细小病毒B19的血清流行率,并将其与其他地区成年人群的血清流行率进行比较。本前瞻性研究使用了1047名孕妇的血样。在采集样本时获取了有关患者年龄、产次、国籍和症状的信息。采用酶联免疫吸附测定(ELISA)技术检测血液中针对细小病毒B19的IgG和IgM抗体。IgG和IgM的总体流行率分别为53.3%和2.2%。非科威特女性的IgG血清阳性率较高,而科威特女性中IgM抗体更为常见。共有17.4%的急性感染患者出现症状。科威特细小病毒B19感染的流行率与其他国家相当。

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