Abiodun Iyanda, Opaleye Oluyinka Oladele, Ojurongbe Olusola, Fagbami Ademola Hezekiah
Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
J Infect Dev Ctries. 2013 Dec 15;7(12):946-50. doi: 10.3855/jidc.3157.
Human parvovirus B19 causes a wide range of complications in pregnant women including abortion, severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. However, there is a dearth of information on the prevalence of the virus among pregnant women in southwestern Nigeria.
Blood samples were collected from 231 pregnant women and screened for antibodies to human parvovirus B19 IgM and IgG using an enzyme immunosorbent assay kits.
Of the 231 women, 31 were in their first trimester, 146 were in their second trimester, and 54 were in their third trimester. Forty-five (20%) were positive for parvovirus B19 IgG antibodies, 10 (4%) were positive for parvovirus B19 IgM antibodies, and 176 (76%) had no detectable parvovirus B19 antibodies. Twenty-eight (19%) of the 146 pregnant women in their second trimester were positive for parvovirus B19 IgG antibody while three (2%) of the 146 were positive for parvovirus B19 IgM antibody.
It is evident that there is a high prevalence of human parvovirus B19 among pregnant women in south-western Nigeria. This suggests that there is an active transmission of the virus in the community; it is therefore necessary to conduct more studies on the virus in pregnant women in Nigeria to ascertain its effect on the fetus.
人细小病毒B19可在孕妇中引发多种并发症，包括流产、严重胎儿贫血、非免疫性胎儿水肿，甚至宫内胎儿死亡。然而，关于尼日利亚西南部孕妇中该病毒的流行情况，相关信息匮乏。
采集了231名孕妇的血样，使用酶联免疫吸附测定试剂盒筛查人细小病毒B19 IgM和IgG抗体。
在这231名女性中，31人处于孕早期，146人处于孕中期，54人处于孕晚期。45人（20%）细小病毒B19 IgG抗体呈阳性，10人（4%）细小病毒B19 IgM抗体呈阳性，176人（76%）未检测到细小病毒B19抗体。146名孕中期孕妇中有28人（19%）细小病毒B19 IgG抗体呈阳性，146人中有3人（2%）细小病毒B19 IgM抗体呈阳性。
显然，尼日利亚西南部孕妇中人细小病毒B19的流行率很高。这表明该病毒在社区中存在活跃传播；因此，有必要对尼日利亚孕妇中的该病毒进行更多研究，以确定其对胎儿的影响。
