Hirokawa M, Shimizu M, Terayama K, Tamai M, Takeda M, Iida M, Manabe T
Department of Pathology, School of Medicine, The University of Tokushima, Japan.
APMIS. 1999 Oct;107(10):951-6. doi: 10.1111/j.1699-0463.1999.tb01496.x.
A bamboo joint-like (BJL) appearance is an endoscopic finding characterized by swollen longitudinal folds transversed by erosive fissures or linear furrows, and it seems to be associated with Crohn's disease (CD). We performed gastroduodenoscopy in 1781 patients, and found BJL lesions in 15 (65.2%) of 23 CD patients and 20 (1.1%) of 1758 non-CD patients. Histological examination of the biopsy specimens showed sharp, fissure-like erosion or mucosal cleft in 7 (50%) out of 14 CD patients and one (20%) out of 5 non-CD patients. All cases with fissure-like erosion or, mucosal cleft revealed lymphoid aggregates, eosinophilic infiltration and edema in the superficial portion of the surrounding lamina propria. Epithelioid granuloma was seen at the base of the fissure-like erosion in two cases with CD. Our results indicated that fissure-like erosion or mucosal cleft in gastric biopsy specimens reflects the BJL appearance, and that such findings may provide a diagnostic clue to CD.
竹节样（BJL）外观是一种内镜检查发现，其特征为纵向皱襞肿胀，并被糜烂性裂隙或线性沟纹横断，似乎与克罗恩病（CD）相关。我们对1781例患者进行了胃十二指肠镜检查，在23例CD患者中有15例（65.2%）发现了BJL病变，在1758例非CD患者中有20例（1.1%）发现了BJL病变。活检标本的组织学检查显示，14例CD患者中有7例（50%）以及5例非CD患者中有1例（20%）出现了尖锐的、裂隙样糜烂或黏膜裂隙。所有出现裂隙样糜烂或黏膜裂隙的病例在周围固有层浅层均显示有淋巴样聚集、嗜酸性粒细胞浸润和水肿。在2例CD患者中，在裂隙样糜烂底部可见上皮样肉芽肿。我们的结果表明，胃活检标本中的裂隙样糜烂或黏膜裂隙反映了BJL外观，并且这些发现可能为CD提供诊断线索。
