Jmor S, El-Atrozy T, Griffin M, Tegos T, Dhanjil S, Nicolaides A
Irvine Laboratory for Cardiovascular Investigation and Research, Imperial College School of Medicine at St Mary's, London, W2 1NY, U.K.
Eur J Vasc Endovasc Surg. 1999 Oct;18(4):315-22. doi: 10.1053/ejvs.1999.0884.
to determine the value of percentage area and diameter reduction in grading ICA stenosis using colour-coded B-mode transverse ultrasonic images.
measurement of the percentage area and diameter reduction of the common carotid, external carotid and internal carotid (at the point of maximum stenosis) were performed, using duplex scanning with colour-flow imaging preoperatively, in 33 patients (six patients were excluded). The duplex measurements were compared to the percentage area and diameter reduction from transverse section of the specimens. Peak systolic (PSV) and end-diastolic velocities (EDV) were measured at the proximal CCA and ICA within the jet of turbulence. A mm scale was placed next to the specimen block, which was captured by video. The area reduction was measured by playing the video and using the same duplex software.
linear-regression analysis of the percentage area reduction of the in vivo against the specimen measurements showed a good linear relationship (r=0.9047). The in vivo duplex measurements had 95% confidence interval (CI) of 8% (95% CI of diameter reduction 5%).
using the gold standard of fixed histological endarterectomy specimen, the results indicate that transverse image obtained with colour B-mode imaging is more appropriate in determining the degree of stenosis.
利用彩色编码B型横向超声图像确定颈内动脉（ICA）狭窄分级中面积和直径减少百分比的价值。
对33例患者（排除6例）术前采用彩色血流成像双功扫描，测量颈总动脉、颈外动脉和颈内动脉（在最大狭窄处）的面积和直径减少百分比。将双功测量结果与标本横截面积和直径减少百分比进行比较。在湍流射流内近端颈总动脉（CCA）和颈内动脉处测量收缩期峰值速度（PSV）和舒张末期速度（EDV）。在标本块旁放置毫米刻度尺，通过视频采集。通过播放视频并使用相同的双功软件测量面积减少情况。
体内面积减少百分比与标本测量值的线性回归分析显示出良好的线性关系（r = 0.9047）。体内双功测量的95%置信区间（CI）为8%（直径减少的95%CI为5%）。
以固定组织学内膜切除术标本的金标准为依据，结果表明彩色B型成像获得的横向图像在确定狭窄程度方面更合适。
