Nishith P, Barabasz A, Barabasz M, Warner D
Washington State University, Pullman 99164, USA.
Am J Clin Hypn. 1999 Jan;41(3):262-8. doi: 10.1080/00029157.1999.10404217.
We sought to determine: 1) whether a simple hypnotic induction with an alprazolam experience derived suggestion could recreate the subjective effects of alprazolam (Xanax), 2) whether the effects of alprazolam are greater than the effects of hypnosis plus this suggestion, and 3) whether the effects of hypnosis plus this suggestion were greater than the relaxation effects produced by hypnosis alone. High and low hypnotizable student volunteer subjects (Ss) ingested 1 mg of alprazolam. A hypnotic suggestion was developed on the basis of their reported reactions to alprazolam. Four days later the same Ss were exposed to hypnosis only and hypnosis plus the alprazolam experience based suggestion conditions in counterbalanced order. Ss exposed to the hypnosis plus suggestion condition demonstrated greater levels of relaxation as measured by the tension-anxiety scale of the Profile of Mood States (POMS) (Eichman & Umstead, 1971) than in the alprazolam condition or the hypnosis only condition. High hypnotizables showed significantly greater levels of relaxation than the low hypnotizables in each of the three conditions (hypnosis plus suggestion, hypnosis only, alprazolam only). EEG data showed frontal and occipital sites were specifically involved in both the alprazolam and the hypnotic suggestion conditions. The findings indicate a basis for the use of hypnosis as a substitute for sedative drug use. Limitations and implications for clinicians are discussed.
1）通过基于阿普唑仑体验得出的建议进行简单的催眠诱导是否能够重现阿普唑仑（佳静安定）的主观效果；2）阿普唑仑的效果是否大于催眠加该建议的效果；3）催眠加该建议的效果是否大于单纯催眠产生的放松效果。高催眠易感性和低催眠易感性的学生志愿者受试者（被试）服用了1毫克阿普唑仑。根据他们报告的对阿普唑仑的反应制定了一条催眠建议。四天后，同样的被试以平衡顺序分别接受仅催眠以及催眠加基于阿普唑仑体验的建议这两种条件。通过情绪状态剖面图（POMS）的紧张 - 焦虑量表（艾克曼和乌姆斯特德，1971）测量发现，接受催眠加建议条件的被试比处于阿普唑仑条件或仅催眠条件下表现出更高水平的放松。在三种条件（催眠加建议、仅催眠、仅阿普唑仑）下，高催眠易感性被试均比低催眠易感性被试表现出显著更高水平的放松。脑电图数据显示，额叶和枕叶部位在阿普唑仑和催眠建议条件下均有特定参与。研究结果表明了使用催眠替代镇静药物的依据。文中还讨论了研究的局限性以及对临床医生的启示。
