Zimmermann T, Albrecht S, von Gagern G
Klinik und Poliklinik für Viszeral-, Thorax- und Gefässchirurgie, Universitätsklinikums, TU Dresden.
Med Klin (Munich). 1999 Oct 15;94 Suppl 3:58-61. doi: 10.1007/BF03042194.
Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S.I.R.S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.
转录因子可调节炎症基因的上调和下调。在重症监护中的硒（SIC）研究范围内，作者将研究转录因子NF-κB和AP-1在全身炎症反应综合征/脓毒症患者中的作用。这些研究的目的是在分子生物学水平上证实亚硒酸钠对脓毒症患者的治疗效果。
