[Eales disease with neurologic manifestation: differential diagnosis of multiple sclerosis. Report of two cases].

BACKGROUND

Eales disease is a condition associating recurrent vitreous and retinal hemorrhage related to retinal periphlebitis. This ophthalmological disease is sometimes associated with central nervous system manifestations.

CASE REPORT

Two patients with Eales disease of the retina developed a progressively worsening neurological deficit several years later.

DISCUSSION

Evidence of multifocal anomalies of the white matter initially suggested a possible association of Earles disease with multiple sclerosis. Pathology findings enable formal differentiation of these two entities. Earles disease with neurological manifestations remains an uncommon condition and constitutes a differential diagnosis of multiple sclerosis.