Dastur D K, Singhal B S
J Neurol Sci. 1976 Mar;27(3):323-45. doi: 10.1016/0022-510x(76)90005-8.
Detailed neuropathologic examination was carried out on 1 case of Eales' disease with CNS involvement, in the form of retinal vasculopathy, followed first by signs of brain stem and cerebellar disease and then by a myelopathy, with death 4 years later from retinal infection. There was mild chronic inflammation in the retina, and sub-total demyelination of one optic nerve. The brain stem and cerebellum showed extensive vasculopathy, with various stages of venous change extending from proliferation and dilatation to haemorrhage, or to thickening with hyalinisation. The perivenular brain tissue, particularly of the cerebellum, often showed demyelination, with relative axon preservation, but no inflammation. Similar, but less pronounced venopathy was seen in the dorsal cord. There was ascending degeneration of Goll's columns and descending degeneration of the lateral columns.
对1例伴有中枢神经系统受累的伊尔斯病进行了详细的神经病理学检查，其表现为视网膜血管病变，先是出现脑干和小脑疾病的体征，随后出现脊髓病，4年后因视网膜感染死亡。视网膜有轻度慢性炎症，一条视神经存在部分脱髓鞘。脑干和小脑显示广泛的血管病变，静脉变化处于不同阶段，从增生、扩张到出血，或增厚伴玻璃样变。血管周围脑组织，尤其是小脑的血管周围脑组织，常出现脱髓鞘，轴突相对保留，但无炎症。在脊髓背侧可见类似但程度较轻的静脉病变。薄束有上行性变性，外侧柱有下行性变性。
