Wright R S, Dyer Z, Liebhaber M I, Kell D L, Harber P
Department of Medicine, University of California, Los Angeles School of Medicine, Los Angeles, California, USA.
Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 1):1758-61. doi: 10.1164/ajrccm.160.5.9904095.
A previously healthy woman developed severe dyspnea and was found to have restrictive lung disease and evidence of alveolitis. Open lung biopsy revealed extrinsic allergic alveolitis (hypersensitivity pneumonitis). The etiology was not initially apparent, but a home inspection showed an unusual mushroom growing in the patient's basement. Air sampling and serum precipitins against the fungal antigens confirmed that Pezizia domiciliana was the cause of the patient's hypersensitivity pneumonitis. This is the first described case of hypersensitivity pneumonitis cause by P. domiciliana. We speculate that unprecedented rainfall and flooding of the patient's basement as a result of El Niño rains produced ideal factors for the growth of this fungus.
一名既往健康的女性出现严重呼吸困难，被发现患有限制性肺病及肺泡炎证据。开胸肺活检显示为外源性过敏性肺泡炎（超敏性肺炎）。病因起初并不明显，但一次家庭检查发现患者地下室生长着一种不寻常的蘑菇。针对真菌抗原的空气采样和血清沉淀素检测证实，家居pezizia是该患者超敏性肺炎的病因。这是首例由家居pezizia引起的超敏性肺炎病例。我们推测，厄尔尼诺降雨导致患者地下室前所未有的降雨和洪水为这种真菌的生长创造了理想条件。
