Nielsen J
Humangenetik. 1975;26(3):215-22. doi: 10.1007/BF00281456.
The purpose of making chromosome investigations of newborn children as well as ethical problems in such studies and in follow-up studies of children with chromosome abnormalities is discussed, and a survey of 6 chromosome studies from a total of 47 145 newborn children is presented. It is stressed that more chromosome studies of newborn children are needed for several reasons, but one of the main reasons is to study the development of children with different chromosome abnormalities, especially those with sex-chromosome abnormalities and compare them with controls.
讨论了对新生儿进行染色体研究的目的以及此类研究和对染色体异常儿童的随访研究中的伦理问题，并介绍了对总共47145名新生儿进行的6项染色体研究的概况。强调由于多种原因，需要对更多新生儿进行染色体研究，但主要原因之一是研究不同染色体异常儿童的发育情况，尤其是性染色体异常儿童，并将他们与对照组进行比较。
