Rossipal E
Z Kinderheilkd. 1975;119(2):143-9.
The incidence of coeliac disease in infants and children was estimated by the number of children born between 1 January 1969 and 31 December 1972 and the number of patients with coeliac disease born during the same period in the area served by the Kinderklinik Graz. The drainage area of the Kinderklinik Graz comprises 10.5% of the population of Austria and 11.1% of the children born in Austria during the period mentioned. The diagnostic criteria for coeliac disease includes evidence of intestinal malabsorption, a subtotal atrophy of the duodenojejunal mucosa and the demonstration of clinical and biochemical response to gluten withdrawal. In all patients born in 1972 a second biopsy was done after a period on gluten free diet and a third biopsy after reintroduction of gluten. The incidence of coeliac disease showed to be 1 in 496. The incidence for girls proved to be 1 in 403 and that for boys 1 in 636. These figures are in good correlation to that reported for Ireland and Switzerland but much higher than those estimated for Britain.
通过统计1969年1月1日至1972年12月31日期间出生的儿童数量以及格拉茨儿童诊所服务区域内同期出生的乳糜泻患者数量，来估算婴幼儿和儿童乳糜泻的发病率。格拉茨儿童诊所的服务区域涵盖奥地利10.5%的人口以及上述时期奥地利出生儿童的11.1%。乳糜泻的诊断标准包括肠道吸收不良的证据、十二指肠空肠黏膜的部分萎缩以及对无麸质饮食的临床和生化反应的证明。对所有1972年出生的患者，在进行无麸质饮食一段时间后进行了第二次活检，并在重新引入麸质后进行了第三次活检。乳糜泻的发病率为496分之一。事实证明，女孩的发病率为403分之一，男孩为636分之一。这些数字与爱尔兰和瑞士报告的数字高度相关，但远高于英国的估计数字。
