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[乳糜泻:176例患者临床资料分析(作者译)]

[Coeliac disease: an analysis of the clinical data in 176 patients (author's transl)].

作者信息

Sacher M, Shmerling D H

出版信息

Wien Klin Wochenschr. 1979 Nov 9;91(21):731-5.

PMID:516743
Abstract

A retrospective analysis of the case histories of 176 infants and children with documented coeliac disease born between 1953 and 1975 revealed the following data: Gluten was introduced into the diet of 49% of these patients at an age of 3 to 4 months. The interval between the introduction of gluten and the appearance of first symptoms was very variable and independent of age, occurring within 4 weeks in 32% and within 2 weeks in 20% of cases. In 13% this interval was 6 to 13 months. 91% of cases presented during the first year of life. Signs were also variable, the most frequent combination being failure to thrive, abnormal stools, anorexia vomiting and abdominal distension. In young infants symptoms tended to be more severe, whilst in children older than 2 years stunting of growth was the most frequent single clinical finding.

摘要

对1953年至1975年间出生的176例有记录的乳糜泻婴幼儿病例史进行回顾性分析,得出以下数据:49%的这些患者在3至4个月大时开始摄入麸质。麸质引入与首次症状出现之间的间隔差异很大,且与年龄无关,32%的病例在4周内出现症状,20%的病例在2周内出现症状。13%的病例此间隔为6至13个月。91%的病例在生命的第一年出现症状。症状也各不相同,最常见的组合是发育不良、大便异常、厌食、呕吐和腹胀。在幼儿中症状往往更严重,而在2岁以上的儿童中,生长发育迟缓是最常见的单一临床发现。

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