Spencer N, Bambang S, Logan S, Gill L
School of Postgraduate Medical Education, University of Warwick, Coventry.
J Epidemiol Community Health. 1999 Aug;53(8):495-8. doi: 10.1136/jech.53.8.495.
To compare the relation of birth weight with socioeconomic status measured by an area-based measure of material deprivation and by the Registrar General's social class.
West Midlands Health Region 1991-93.
Retrospective cohort study.
Birthweight data by enumeration district deciles ranked by Townsend Deprivation Index based on 1991 census data for all live births in the West Midlands Health Region were studied in three consecutive whole year birth cohorts, 1991 to 1993 and by Registrar General's social class in a 10% sample of live births (within marriage and jointly registered, provided by the Office of National Statistics) in the same region for the same period. Estimated proportions of births < 2500 g and < 3500 g "attributable" to social inequalities were compared for both socioeconomic status measures. The proportion of infants in each birthweight group were calculated for both measures. Relative risk (95% confidence intervals) of birth in each birthweight group for lowest versus highest socioeconomic status groups were calculated.
The estimated proportions of births < 2500 g "attributable" to social inequalities were 30% using the area-based measure and 27% using the Registrar General's social class. For births < 3500 g, the estimated proportions were 12% for the area-based measure and 7% for social class. There was a positive linear relation between the proportion of babies weighing > or = 3500 g and increasing socio-economic status measured by either method. Gradients in the opposite direction were noted for the proportion of babies born in the other birth weight groups. Relative risk of birth weight < 3500 g was 1.30 (95% CIs 1.28, 1.32) for most versus least deprived decile and 1.17 (95% CIs 1.10, 1.25) for social class V versus I. For birth weight < 2500 g the risks were 1.99 (95% CIs 1.85, 2.18) and 2.04 (95% CIs 1.53, 2.73) respectively and for birth weight < 1500 g, 2.11 (95% CIs 1.73, 2.57) for most versus least deprived decile (numbers too small for analysis in the Office of National Statistics sample).
A substantial proportion of births < 2500 g and < 1500 g are statistically "attributable" to social inequality. The results demonstrate that, using either socioeconomic measure, the likelihood of being born weighing > or = 3500 g, the most advantageous group, is substantially greater in the socially advantaged. Using the area-based measure, an estimated 12% of births < 3500 g could be ascribed to social inequalities whereas the same figure using social class was 7%. These findings suggest that this proxy measure of socioeconomic status may be a better discriminator in the study of pregnancy outcomes in this population than classification by occupational social class. Another advantage is its almost universal availability in routine records and its universal population coverage.
比较出生体重与社会经济地位之间的关系,社会经济地位通过基于地区的物质匮乏衡量指标以及总登记官的社会阶层来衡量。
西米德兰兹郡健康区域,1991 - 1993年。
回顾性队列研究。
根据汤森贫困指数,按照普查区十分位数对西米德兰兹郡健康区域1991年至1993年连续三个全年出生队列中的所有活产儿的出生体重数据进行研究,并根据总登记官的社会阶层对同期该区域10%的活产儿样本(婚内且共同登记,由国家统计局提供)进行研究。比较了两种社会经济地位衡量指标下,出生体重<2500克和<3500克的出生数中“归因于”社会不平等的估计比例。计算了两种衡量指标下每个出生体重组中婴儿的比例。计算了社会经济地位最低组与最高组在每个出生体重组中的出生相对风险(95%置信区间)。
基于地区的衡量指标显示,出生体重<2500克的出生数中“归因于”社会不平等的估计比例为30%,而根据总登记官的社会阶层这一比例为27%。对于出生体重<3500克的情况,基于地区的衡量指标估计比例为12%,社会阶层为7%。无论采用哪种方法衡量社会经济地位,出生体重≥3500克的婴儿比例与社会经济地位的提高呈正线性关系。在其他出生体重组中出生的婴儿比例呈现相反方向的梯度。社会经济地位最贫困十分位数与最不贫困十分位数相比,出生体重<3500克的相对风险为1.30(95%置信区间1.28, 1.32),社会阶层V与I相比为1.17(95%置信区间1.10, 1.25)。对于出生体重<2500克,风险分别为1.99(95%置信区间1.85, 2.18)和2.04(95%置信区间1.53, 2.73),对于出生体重<1500克,社会经济地位最贫困十分位数与最不贫困十分位数相比为2.11(95%置信区间1.73, 2.57)(国家统计局样本中数量过少无法分析)。
相当比例的出生体重<2500克和<1500克在统计学上“归因于”社会不平等。结果表明,无论采用哪种社会经济衡量指标,出生时体重≥3500克(最有利的组)的可能性在社会优势群体中显著更高。基于地区的衡量指标显示,估计12%的出生体重<3500克可归因于社会不平等,而使用社会阶层时这一数字为7%。这些发现表明,在该人群的妊娠结局研究中,这种社会经济地位的替代衡量指标可能比职业社会阶层分类更具区分性。另一个优点是它几乎普遍存在于常规记录中且覆盖全体人群。