Lim J K, Jensen G K
J Dent Res. 1975 May-Jun;54(3):615-25. doi: 10.1177/00220345750540033501.
Weanling rats were administered 20, 380, and 20,000 ppm F as clear precipitatefree SnF2 solutions. Equivalent ppm F as NaF solution was similarly administered for comparison. The rats were autopsied at the end of the study for histological examination of kidney, liver, and incisors. The pathognomonic manifestations were correlated with the plasma F levels.
给断乳大鼠分别灌胃20、380和20000 ppm氟,以清澈无沉淀的氟化亚锡溶液形式给予。作为对照,以类似方式给予等量ppm氟的氟化钠溶液。在研究结束时对大鼠进行解剖,以对肾脏、肝脏和门齿进行组织学检查。将特征性表现与血浆氟水平相关联。