Skibsted L, Brocks V
H:S Rigshospitalet, ultralydklinikken.
Ugeskr Laeger. 1999 Oct 11;161(41):5674-8.
The incidence of multiple pregnancy has increased by 1.7 times from 1980-1994. Twenty-five percent of all twins are monochorionic diamnionic. The perinatal mortality of monochorionic twins is five times greater than that found in dichorionic twins and the morbidity is eight times greater. The increase in morbidity is due to prematurity, cerebral lesions and congenital malformations. One of the reasons for the increased morbidity is twin-twin transfusion syndrome (TTTS). TTTS occurs in 10-30% of monochorionic twins. TTTS can be treated by either amniocenteses or by lasercoagulation of anastomoses in the placenta. This paper describes the syndrome and reviews the literature. A multination randomized study is necessary to decide which treatment should be preferred.
1980年至1994年间，多胎妊娠的发生率增长了1.7倍。所有双胞胎中有25%为单绒毛膜双羊膜囊。单绒毛膜双胎的围产期死亡率是双绒毛膜双胎的五倍，发病率则是八倍。发病率增加的原因是早产、脑部病变和先天性畸形。发病率增加的原因之一是双胎输血综合征（TTTS）。TTTS发生于10%至30%的单绒毛膜双胎中。TTTS可通过羊膜腔穿刺或胎盘吻合血管激光凝固术进行治疗。本文描述了该综合征并回顾了相关文献。有必要开展一项多国随机研究来确定哪种治疗方法更可取。
