Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland, School of Medicine, Baltimore, MD, USA.
J Perinat Med. 2011 Mar;39(2):107-12. doi: 10.1515/jpm.2010.147. Epub 2010 Dec 13.
Twin-to-twin transfusion syndrome (TTTS) is a severe complication of monochorionic (MC) twin pregnancies, characterized by the development of unbalanced chronic blood transfer from one twin, defined as donor twin, to the other, defined as recipient, through placental anastomoses. If left untreated, TTTS is associated with very high perinatal mortality and morbidity rates, due to a combination of fetal and/or obstetric complications. The reported prevalence is 10-15% of all MC twins, or about 1 in 2000 pregnancies. This consensus document reviews available evidence and offers practical guidance to clinicians by providing recommendations on various aspects concerning diagnosis and management of TTTS.
双胎输血综合征（TTTS）是单绒毛膜（MC）双胎妊娠的严重并发症，其特征为通过胎盘吻合从一个胎儿（定义为供体胎儿）向另一个胎儿（定义为受体胎儿）发生不平衡的慢性血液转移。如果不进行治疗，TTTS 由于胎儿和/或产科并发症的综合作用，围产期死亡率和发病率非常高。其报告发生率为所有 MC 双胎妊娠的 10-15%，即大约每 2000 次妊娠中有 1 例。本共识文件回顾了现有证据，并通过提供有关 TTTS 诊断和管理各个方面的建议，为临床医生提供实用指导。
