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细粒棘球绦虫胚膜感染小鼠实验性原发性包虫病血清学反应的动力学(作者译)

[Kinetics of the serological response in the experimental primary hydatid disease of mice infected with Echinococcus granulosus embryophores (author's transl)].

作者信息

Torres Rodriguez J M, Wisnivesky C

出版信息

Ann Parasitol Hum Comp. 1978 Sep-Oct;53(5):479-86.

PMID:105664
Abstract

A serological response kinetics study was carried out in CF-1 mice orally infected with Echinococcus granulosus embryophores using immuno-electrophoresis, double diffusion, latex agglutination and passive hemagglutination. Starting from the 76th day after the infection, serum antibodies reach the minimum detectable level by immunoelectrophoresis test. Band number 5, now considered as specific for E. granulosus, was proved to be the first precipitating system exhibited in this test. Double diffusion, latex agglutination and passive hemagglutination tests developed positive results later (125--144 days after infection). Correlation between serologic and anatomo-pathologic findings suggest that hydatid cyst fluid presence in the cysts is necessary for circulating antibodies production.

摘要

采用免疫电泳、双向扩散、乳胶凝集和被动血凝试验,对口服感染细粒棘球绦虫原头蚴的CF-1小鼠进行了血清学反应动力学研究。感染后第76天起,血清抗体通过免疫电泳试验达到最低可检测水平。现被认为是细粒棘球绦虫特异性的第5条带,被证明是该试验中出现的第一个沉淀系统。双向扩散、乳胶凝集和被动血凝试验后来出现阳性结果(感染后125 - 144天)。血清学和解剖病理学结果之间的相关性表明,囊肿中存在棘球蚴囊液是产生循环抗体所必需的。

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