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细粒棘球绦虫胚膜感染小鼠实验性原发性包虫病血清学反应的动力学(作者译)

[Kinetics of the serological response in the experimental primary hydatid disease of mice infected with Echinococcus granulosus embryophores (author's transl)].

作者信息

Torres Rodriguez J M, Wisnivesky C

出版信息

Ann Parasitol Hum Comp. 1978 Sep-Oct;53(5):479-86.

PMID:105664
Abstract

A serological response kinetics study was carried out in CF-1 mice orally infected with Echinococcus granulosus embryophores using immuno-electrophoresis, double diffusion, latex agglutination and passive hemagglutination. Starting from the 76th day after the infection, serum antibodies reach the minimum detectable level by immunoelectrophoresis test. Band number 5, now considered as specific for E. granulosus, was proved to be the first precipitating system exhibited in this test. Double diffusion, latex agglutination and passive hemagglutination tests developed positive results later (125--144 days after infection). Correlation between serologic and anatomo-pathologic findings suggest that hydatid cyst fluid presence in the cysts is necessary for circulating antibodies production.

摘要

采用免疫电泳、双向扩散、乳胶凝集和被动血凝试验,对口服感染细粒棘球绦虫原头蚴的CF-1小鼠进行了血清学反应动力学研究。感染后第76天起,血清抗体通过免疫电泳试验达到最低可检测水平。现被认为是细粒棘球绦虫特异性的第5条带,被证明是该试验中出现的第一个沉淀系统。双向扩散、乳胶凝集和被动血凝试验后来出现阳性结果(感染后125 - 144天)。血清学和解剖病理学结果之间的相关性表明,囊肿中存在棘球蚴囊液是产生循环抗体所必需的。

相似文献

1
[Kinetics of the serological response in the experimental primary hydatid disease of mice infected with Echinococcus granulosus embryophores (author's transl)].细粒棘球绦虫胚膜感染小鼠实验性原发性包虫病血清学反应的动力学(作者译)
Ann Parasitol Hum Comp. 1978 Sep-Oct;53(5):479-86.
2
[Contributions to the immunodiagnosis of echinococcosis (author's transl)].[棘球蚴病免疫诊断的研究(作者译)]
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[Immunological humoral response in mice experimentally infected with Echinococcus granulosus, preliminary result of kinetic observation].[实验感染细粒棘球绦虫小鼠的免疫体液反应,动力学观察的初步结果]
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1989;7(3):170-3.
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Immunological response to experimental echnococcosis in Meriones unguiculatus.长爪沙鼠对实验性棘球蚴病的免疫反应。
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Preparation and evaluation of antigens for use in the serologic diagnosis of human hydatid disease. II. Isolation and characterization from extracts of cysts of Echinococcus multilocularis of serologically reactive elements found in hydatid fluid of Echinococcus granulosus.用于人类包虫病血清学诊断的抗原的制备与评估。II. 从多房棘球绦虫囊肿提取物中分离并鉴定细粒棘球绦虫包虫液中发现的血清学反应性成分。
J Immunol. 1966 May;96(5):822-8.
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Evaluation of five immunodiagnostic techniques in echinococcosis patients.棘球蚴病患者五种免疫诊断技术的评估
Bull World Health Organ. 1981;59(5):767-72.
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Isolation of the most immunoreactive antigenes of echinococcus granulosus from sheep hydatid fluid.从绵羊包虫液中分离出细粒棘球绦虫最具免疫反应性的抗原。
J Immunol. 1975 Nov;115(5):1459-63.
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Detection of antibodies against Echinococcus granulosus arc 5 antigens by double diffusion test.用双向扩散试验检测抗细粒棘球绦虫5号抗原的抗体
Trans R Soc Trop Med Hyg. 1978;72(3):226-9. doi: 10.1016/0035-9203(78)90198-0.
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Reaginic antibodies in dogs infected with Echinococcus granulosus.感染细粒棘球绦虫的犬体内的反应素抗体。
Immunology. 1971 Apr;20(4):451-5.
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Detection of specific hydatid antigens and antibodies in serum and urine of experimentally infected sheep.在实验感染绵羊的血清和尿液中检测特定的包虫抗原和抗体。
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引用本文的文献

1
Concepts in immunology and diagnosis of hydatid disease.包虫病的免疫学与诊断概念
Clin Microbiol Rev. 2003 Jan;16(1):18-36. doi: 10.1128/CMR.16.1.18-36.2003.