Peters A, Perz S, Döring A, Stieber J, Koenig W, Wichmann H E
GSF-National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany.
Am J Epidemiol. 1999 Nov 15;150(10):1094-8. doi: 10.1093/oxfordjournals.aje.a009934.
This paper assesses whether air pollution increases resting heart rates in 2,681 men and women aged 25-64 years who participated in the MONICA (monitoring of trends and determinants in cardiovascular disease) Augsburg cohort. Increases in heart rate were observed during the air pollution episode in January 1985 compared with non-episode days adjusted for cardiovascular risk factors and meteorologic parameters. Consistently, heart rates were also elevated at high concentrations of sulfur dioxide, total suspended particulates, or carbon monoxide. Acceleration in heart rates indicates an altered autonomic control of the heart in association with air pollution, which may contribute to the observed health effects in association with air pollution.
本文评估空气污染是否会使参与了心血管疾病趋势和决定因素监测(MONICA)奥格斯堡队列研究的2681名年龄在25至64岁之间的男性和女性的静息心率升高。与根据心血管危险因素和气象参数进行调整后的非污染日相比,在1985年1月的空气污染事件期间观察到心率升高。同样,在高浓度的二氧化硫、总悬浮颗粒物或一氧化碳情况下,心率也会升高。心率加快表明与空气污染相关的心脏自主控制发生了改变,这可能导致了与空气污染相关的健康影响。