Joynson D H, Howells C H, Liddington R, Williams A
J Hyg (Lond). 1975 Aug;75(1):87-90. doi: 10.1017/s0022172400047094.
An investigation into the cause of bacterial contamination of bottles of noninjectable water has been reported. A method of monitoring such bottles has also been described. The roles played by autoclave spray-cooling water and inadequate bottle seals in the contamination of fluids have been examined. Possible methods of reducing the risk of contamination are discussed and the design of an improved method of closure of sterile bottled fluids is stressed. Bacteriological examination is shown to be a more accurate index of the true rate of contamination than measurement of dye concentrations of bottle contents.
据报道，已对非注射用水瓶细菌污染的原因展开调查。还描述了一种监测此类水瓶的方法。研究了高压灭菌喷雾冷却水和瓶盖密封不当在液体污染中所起的作用。讨论了降低污染风险的可能方法，并强调了改进无菌瓶装液体密封方法的设计。结果表明，细菌学检查比测量瓶内液体的染料浓度更能准确反映实际污染率。
