急性腹泻不同喂养速率的随机试验。
Randomised trial of different rates of feeding in acute diarrhoea.
作者信息
Wan C, Phillips M R, Dibley M J, Liu Z
机构信息
Departments of Pediatrics and Clinical Epidemiology, West China University of Medical Sciences, Chengdu 610041, People's Republic of China.
出版信息
Arch Dis Child. 1999 Dec;81(6):487-91. doi: 10.1136/adc.81.6.487.
OBJECTIVE
To compare the effect of different feeding frequencies on the speed of recovery from diarrhoea.
METHODS
A randomised, non-blinded trial provided 0.452 MJ/kg/day as either 6 or 12 feeds of cows' milk each day to 262 hospitalised male infants aged 3-12 months with acute diarrhoea. Stool frequency, stool weight, body weight, and diarrhoea complications were monitored until recovery or for 14 days.
RESULTS
A proportional hazards regression model controlling for age, diarrhoea aetiology, and severity of dehydration on admission revealed that the frequently fed group had a significantly shorter duration of diarrhoea (hazards ratio, 1.29; 95% confidence interval, 1.002 to 1.653). Frequently fed infants had a significantly greater weight gain and significantly lower faecal frequency and faecal weight.
CONCLUSIONS
Breast feeding remains the preferred method of feeding infants with acute diarrhoea, but feeding cows' milk to adequately nourished infants with acute diarrhoea is safe and is more rapidly effective if provided in frequent feeds with low energy loads.
目的
比较不同喂养频率对腹泻恢复速度的影响。
方法
一项随机、非盲试验，为262名3至12个月大患急性腹泻的住院男婴，每天提供0.452兆焦/千克的能量，以每日6次或12次的频率喂食牛奶。监测粪便频率、粪便重量、体重和腹泻并发症，直至恢复或持续14天。
结果
一个对年龄、腹泻病因和入院时脱水严重程度进行控制的比例风险回归模型显示，频繁喂食组的腹泻持续时间显著缩短（风险比为1.29；95%置信区间为1.002至1.653）。频繁喂食的婴儿体重增加显著更多，粪便频率和粪便重量显著更低。
结论
母乳喂养仍然是喂养急性腹泻婴儿的首选方法，但对于营养充足的急性腹泻婴儿，喂食牛奶是安全的，并且如果以低能量负荷频繁喂食，恢复效果更快。
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