Imai Y, Ohkubo T, Tsuji I, Hozawa A, Nagai K, Kikuya M, Aihara A, Sekino M, Michimata M, Matsubara M, Ito S, Satoh H, Hisamichi S
Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Science, and Medicine, Sendai, Japan.
Hypertens Res. 1999 Nov;22(4):261-72. doi: 10.1291/hypres.22.261.
To examine the relationships between casual, ambulatory and home blood pressure measurements in the general population, these measurements were obtained in 1,695 of 3,744 subjects aged 20 yr or older in Ohasama, Japan. Of these 1,695 subjects, 1,207 measured their home blood pressure more than 14 times in each of the morning and evening (881 untreated subjects including normotensives and untreated hypertensives, 56.4 +/- 11.5 yr of age; 326 treated subjects, 66.0 +/- 9.2 yr of age). We analyzed data in these 1,207 subjects, examining the distribution of each measurement, the relationships among measurements, and the factors affecting the blood pressure differences among the measurements. For systolic pressure, the casual measurement was the highest among the methods examined. The daytime ambulatory measurement was significantly higher than morning and evening home measurements. Morning home measurements were significantly higher than those in the evening. For diastolic pressure, however, the morning home measurement was the highest among the methods examined. Short-term pressure variability (standard deviation and variation coefficient of ambulatory measurements) was greater than long-term pressure variability (standard deviation and variation coefficient of home measurements). The pressure variability in treated subjects was greater than that in untreated subjects. The correlation between casual pressure and the other pressures was not as strong (r<0.567). Among the relationships between ambulatory and home measurements, the strongest correlation was observed between the 24-h ambulatory measurement and the morning home measurement (r=0.738) in untreated subjects. The morning home measurement was highly correlated with the evening home measurement (r>0.814). The differences among the methods examined were affected by blood pressure level and age. It should be noted that in elderly and treated subjects, blood pressure measurement using one method does not necessarily correlate with that obtained using the other methods. This information is useful for the estimation of the value of one type of blood pressure measurement from values obtained with other methods.
为研究普通人群中偶测血压、动态血压与家庭血压测量值之间的关系,在日本大岛地区3744名20岁及以上的受试者中,对其中1695人进行了这些测量。在这1695名受试者中,有1207人在早晨和晚上各自测量家庭血压超过14次(881名未治疗受试者,包括血压正常者和未治疗的高血压患者,年龄为56.4±11.5岁;326名已治疗受试者,年龄为66.0±9.2岁)。我们分析了这1207名受试者的数据,研究了每种测量值的分布、测量值之间的关系以及影响测量值之间血压差异的因素。对于收缩压,在所研究的测量方法中,偶测血压最高。白天动态血压测量值显著高于早晨和晚上的家庭血压测量值。早晨家庭血压测量值显著高于晚上的测量值。然而,对于舒张压,在所研究的测量方法中,早晨家庭血压测量值最高。短期血压变异性(动态血压测量的标准差和变异系数)大于长期血压变异性(家庭血压测量的标准差和变异系数)。已治疗受试者的血压变异性大于未治疗受试者。偶测血压与其他血压之间的相关性不强(r<0.567)。在动态血压与家庭血压测量值之间的关系中,未治疗受试者中24小时动态血压测量值与早晨家庭血压测量值之间的相关性最强(r = 0.738)。早晨家庭血压测量值与晚上家庭血压测量值高度相关(r>0.814)。所研究测量方法之间的差异受血压水平和年龄的影响。应当注意的是,在老年受试者和已治疗受试者中,使用一种方法测量的血压不一定与使用其他方法获得的血压相关。这些信息对于根据其他方法获得的值来估计一种血压测量值的数值很有用。