Lundgren J, Olofsson J
Clin Otolaryngol Allied Sci. 1979 Feb;4(1):13-23. doi: 10.1111/j.1365-2273.1979.tb01748.x.
Postoperative pharyngocutaneous fistula formation is a troublesome complication in head and neck surgery and occurred in 8 out of 53 patients following a total laryngectomy (15%). The incidence falls within the lower range of that reported in the literature (6-66%). Different factors which may influence the formation of fistulae were analysed. Factors which seem to increase fistula formation are previous full dose radiotherapy (Co60), residual carcinoma and surgical technique.
术后咽皮瘘形成是头颈外科手术中一个棘手的并发症，在53例全喉切除术后患者中有8例发生（15%）。该发生率处于文献报道范围的下限（6%-66%）。分析了可能影响瘘形成的不同因素。似乎会增加瘘形成的因素有既往全量放疗（钴60）、残留癌和手术技术。
