Sullivan J R, Ungar B, Hicks J D, Hurley T H
Aust N Z J Med. 1975 Aug;5(4):347-55. doi: 10.1111/j.1445-5994.1975.tb03270.x.
The clinical and pathological features of histiocytic medullary reticulosis (HMR) are described in five patients. Treatment by splenectomy and the MOPP routine resulted in a transient improvement in platelet and neutrophil counts and resolution of anaemia and apparent prolongation of survival in two of the five patients. The relationship of HMR to other histiocytic disorders is discussed. HMR is defined as a unique malignant histiocytosis in which malignant histiocytes engage in phagocytosis of eryrhrocytes, leucocytes and platelets.
本文描述了5例组织细胞性髓性网状细胞增生症(HMR)患者的临床和病理特征。5例患者中有2例接受脾切除术和MOPP方案治疗后,血小板和中性粒细胞计数短暂改善,贫血症状缓解,生存期明显延长。文中讨论了HMR与其他组织细胞疾病的关系。HMR被定义为一种独特的恶性组织细胞增生症,其中恶性组织细胞会吞噬红细胞、白细胞和血小板。