Dunlap C L
Department of Oral and Maxillofacial Pathology, University of Missouri, Kansas City, School of Dentistry, 64108, USA.
Semin Diagn Pathol. 1999 Nov;16(4):293-6.
The odontogenic fibroma is a rare tumor that has generated controversy, perhaps disproportionately to its importance in the family of odontogenic tumors. The clinical and radiographic features are well documented but the histologic aspects have generated controversy. The behavior is benign, and published accounts indicate a low recurrence rate following treatment by curettage. The tumor recognized by the World Health Organization (WHO) is the legitimate odontogenic fibroma. Histologic variants include the granular cell type and the hybrid odontogenic fibroma giant cell-like tumor. Although the extraosseous "peripheral" odontogenic fibroma presents as a gingival enlargement clinically indistinguishable from other gingival lesions, its histomorphology is similar to the central tumor. A normal dental follicle around the crown of an unerupted tooth may histologically mimic the odontogenic fibroma and other odontogenic tumors.
牙源性纤维瘤是一种罕见的肿瘤,它引发了诸多争议,或许与其在牙源性肿瘤家族中的重要性不相称。其临床和影像学特征已有充分记录,但组织学方面却存在争议。该肿瘤行为良性,已发表的报道显示刮除术后复发率较低。世界卫生组织(WHO)认定的肿瘤才是真正的牙源性纤维瘤。组织学变异型包括颗粒细胞型和混合性牙源性纤维瘤巨细胞样肿瘤。尽管骨外型“外周性”牙源性纤维瘤在临床上表现为牙龈肿大,与其他牙龈病变难以区分,但其组织形态学与中央型肿瘤相似。未萌出牙冠周围的正常牙囊在组织学上可能会模仿牙源性纤维瘤及其他牙源性肿瘤。