Ghorbani Farhad, Motazedian Jamaledin, Khaghaninejad Mohammad Saleh, Keshvari Haleh, Paknahad Maryam
Oral and Maxillofacial Surgery Shiraz University of Medical Sciences Shiraz Iran.
Oral and Maxillofacial Pathologist Rajaei Hospital Shiraz Iran.
Clin Case Rep. 2025 Aug 8;13(8):e70761. doi: 10.1002/ccr3.70761. eCollection 2025 Aug.
Central odontogenic fibroma (COF) is a rare benign tumor originating from periodontal tissues. Although it typically grows slowly and remains asymptomatic, COF can cause significant complications when neglected, including displacement of teeth, bone destruction, and even life-threatening airway obstruction.
中央型牙源性纤维瘤(COF)是一种起源于牙周组织的罕见良性肿瘤。尽管它通常生长缓慢且无症状,但如果被忽视,COF可能会导致严重并发症,包括牙齿移位、骨质破坏,甚至危及生命的气道阻塞。