Barker B F
University of Missouri-Kansas City, School of Dentistry, 64108, USA.
Semin Diagn Pathol. 1999 Nov;16(4):297-301.
The odontogenic myxoma is an uncommon tumor that has the potential for extensive bony destruction, extension into surrounding structures, and a relatively high recurrence rate. Treatment often requires bone resection. The bland histologic features of a monotonous proliferation of a loose, mesenchymal fibrous tissue that lacks atypia may easily lead to a misdiagnosis. The primitive dental pulp, the dental papilla, and the tooth follicle are histologically similar to myxoma. These soft tissue fragments often separate from extracted developing teeth that are submitted to the pathologist and may easily be misinterpreted as an odontogenic myxoma. The pathologist must have good clinical and radiographic correlation to avoid a misdiagnosis and to prevent unnecessary additional surgery.
牙源性黏液瘤是一种罕见肿瘤,有导致广泛骨质破坏、侵犯周围结构及相对较高复发率的可能。治疗通常需要进行骨切除。其组织学特征为缺乏异型性的疏松间叶纤维组织呈单调增殖,这种平淡的表现很容易导致误诊。原始牙髓、牙乳头和牙囊在组织学上与黏液瘤相似。这些软组织碎片常从提交给病理学家的拔除的发育中牙齿上分离,可能很容易被误诊为牙源性黏液瘤。病理学家必须具备良好的临床与影像学相关性,以避免误诊并防止不必要的额外手术。