Monfort-Gouraud M, Hamza A, Nacer K, Barjonnet G, Tranie V, Devanlay M, Sauvageon G
Service de pédiatrie, centre hospitalier de Coulommiers, France.
Arch Pediatr. 1999 Nov;6(11):1191-2. doi: 10.1016/s0929-693x(00)86302-2.
An adolescent admitted to hospital because of an obvious convulsion seizure presented with a high level of serum macroaspartate aminotransferase. This macroaspartate aminotransferase was discovered by chance when blood tests were made.
Macroaspartate aminotransferase is a persistent, benign phenomenon, probably not congenital, discovered either in healthy patients, or in adults suffering from malignancies or autoimmune diseases. Macroenzymes have been identified as a cause of benign increase in a number of serum enzymes, like macroamylase serum levels. The macroenzyme is often an immunoglobulin G-complexed enzyme.
It is important for clinicians to be aware of their existence in order to avoid unnecessary procedures. It is important that the patient is informed of the macroaspartate aminotransferase and that the same is stated in his health record.
一名青少年因明显的惊厥发作入院，其血清中发现高水平的巨天冬氨酸转氨酶。这种巨天冬氨酸转氨酶是在进行血液检查时偶然发现的。
巨天冬氨酸转氨酶是一种持续存在的良性现象，可能并非先天性，在健康患者、患有恶性肿瘤或自身免疫性疾病的成年人中均可发现。巨酶已被确认为多种血清酶良性升高的原因，如血清巨淀粉酶水平升高。巨酶通常是一种与免疫球蛋白G结合的酶。
临床医生了解它们的存在很重要，这样可以避免不必要的检查。告知患者有关巨天冬氨酸转氨酶的情况并记录在其健康档案中也很重要。
