Patural H, Teyssier G, Pozzeto B
Service de réanimation pédiatrique et néonatologie, CHU de Saint-Etienne, France.
Arch Pediatr. 1999 Nov;6(11):1205-11. doi: 10.1016/S0929-693X(00)86306-X.
Enterovirus infections in childhood (echoviruses, coxsackie viruses A and B, unclassified enteroviruses) are varied, nonspecific and benign (except for poliovirus infections). However, in infants, they may lead to severe neurological or cardiac lesions. In neonates, enterovirus infections are difficult to distinguish from late-onset bacterial infection. Maternal-fetal or postnatal transmission can induce early spontaneous abortions or severe neonatal infections. Diagnosis is usually based on viral cultures and, in recent years, on PCR techniques. At the present time, no potential effective drug is available: intravenous immunoglobulins, immunization or anti-proteases may be of interest.
儿童肠道病毒感染（埃可病毒、柯萨奇病毒A和B、未分类肠道病毒）多种多样，症状不具特异性且一般为良性（脊髓灰质炎病毒感染除外）。然而，在婴儿中，它们可能导致严重的神经或心脏损害。在新生儿中，肠道病毒感染很难与迟发性细菌感染区分开来。母婴传播或产后传播可导致早期自然流产或严重的新生儿感染。诊断通常基于病毒培养，近年来也基于PCR技术。目前，尚无潜在有效的药物：静脉注射免疫球蛋白、免疫接种或抗蛋白酶可能值得关注。
