Suppr超能文献

产时连续监测pH值、氧分压、二氧化碳分压和血氧饱和度。

Continuous intrapartum pH, pO2, pCO2, and SpO2 monitoring.

作者信息

McNamara H M, Dildy G A

机构信息

Department of Obstetrics and Gynecology, McGill University, Canada.

出版信息

Obstet Gynecol Clin North Am. 1999 Dec;26(4):671-93. doi: 10.1016/s0889-8545(05)70106-6.

Abstract

The goal of intrapartum surveillance and its further development is better patient care for both the fetus and the gravida. A normal FHR pattern is usually associated with the delivery of a normal well-oxygenated infant; however, a nonreassuring FHR is not always associated with the delivery of a compromised infant. This situation has led to an increase in unnecessary obstetric interventions in the form of a rising cesarean section rate. Fetal scalp sampling was developed in an attempt to improve the predictive value of electronic FHR monitoring, but because this technique is not widely used, management decisions are frequently made using FHR patterns alone. Much research has been performed in the search for a continuous biochemical measurement of fetal status, including continuous pH, pO2, or pCO2 and various combinations of these methodologies. None of these measurements are used in current clinical practice, mainly owing to technical problems and difficulties associated with the continuous direct measurement of these parameters in fetal blood throughout labor. The promising new field of fetal pulse oximetry has the potential to provide reliable, meaningful, and reproducible data as shown in early cross-sectional studies and more recent longitudinal studies. By identifying developing hypoxia, this technology may reduce the uncertainty associated with electronic FHR monitoring. Fetal pulse oximetry may also provide critical information relating to the detection and management of the hypoxic fetus. Any new method of intrapartum fetal monitoring requires careful evaluation to assess its potential value before its introduction into clinical practice. The use of fetal SpO2 monitoring in the presence of a nonreassuring FHR pattern is being examined in a multicenter randomized controlled trial. This study will address the question of whether supplementary monitoring of fetal SpO2 levels can lead to a reduction in the cesarean section rate for fetal distress. The available data on fetal noninvasive pulse oximetry have been obtained from a combination of well-designed cohort studies (level II-2 evidence) or from earlier multiple time series (level II-3 evidence). The results from the US Multicenter Trial (level I evidence) should provide a significant addition to current evidence. A continuous fetal noninvasive monitor measuring fetal oxygenation directly could lead to an improvement in the sensitivity and specificity of fetal surveillance. This improvement could ultimately result in a reduction in unnecessary interventions by differentiating hypoxic fetuses from nonhypoxic fetuses and, more importantly, may lead to earlier intervention for fetuses in danger of serious compromise.

摘要

产时监测及其进一步发展的目标是为胎儿和孕妇提供更好的医疗护理。正常的胎心率模式通常与娩出正常、氧合良好的婴儿相关;然而,胎心率异常并不总是与娩出受损婴儿相关。这种情况导致了以剖宫产率上升形式出现的不必要产科干预的增加。胎儿头皮血采样的发展是为了提高电子胎心率监测的预测价值,但由于该技术未被广泛应用,管理决策常常仅依据胎心率模式做出。为寻找连续生化测量胎儿状态的方法,人们开展了大量研究,包括连续测量pH、pO2或pCO2以及这些方法的各种组合。目前这些测量方法均未用于临床实践,主要是因为技术问题以及在整个分娩过程中对胎儿血液中这些参数进行连续直接测量存在困难。胎儿脉搏血氧饱和度测定这一有前景的新领域,在早期横断面研究和近期纵向研究中已显示出有提供可靠、有意义且可重复数据的潜力。通过识别正在发展的缺氧情况,这项技术可能会减少与电子胎心率监测相关的不确定性。胎儿脉搏血氧饱和度测定还可能为缺氧胎儿的检测和管理提供关键信息。任何新的产时胎儿监测方法在引入临床实践之前都需要仔细评估以确定其潜在价值。一项多中心随机对照试验正在研究在胎心率异常模式下使用胎儿SpO2监测的情况。这项研究将解决胎儿SpO2水平的补充监测是否能降低胎儿窘迫剖宫产率这一问题。关于胎儿无创脉搏血氧饱和度测定的现有数据来自精心设计的队列研究(II - 2级证据)或早期多次时间序列研究(II - 3级证据)的综合。美国多中心试验(I级证据)的结果应会为当前证据增添重要内容。一种直接测量胎儿氧合情况的连续胎儿无创监测仪可能会提高胎儿监测的敏感性和特异性。这种提高最终可能会通过区分缺氧胎儿和非缺氧胎儿减少不必要的干预,更重要的是,可能会对有严重受损危险的胎儿进行更早的干预。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验