2000年的SWISS-PROT蛋白质序列数据库及其补充数据库TrEMBL。
The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.
作者信息
Bairoch A, Apweiler R
机构信息
Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva 4, Switzerland.
出版信息
Nucleic Acids Res. 2000 Jan 1;28(1):45-8. doi: 10.1093/nar/28.1.45.
SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include format and content enhancements, cross-references to additional databases, new documentation files and improvements to TrEMBL, a computer-annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDSs) in the EMBL Nucleotide Sequence Database, except the CDSs already included in SWISS-PROT. We also describe the Human Proteomics Initiative (HPI), a major project to annotate all known human sequences according to the quality standards of SWISS-PROT. SWISS-PROT is available at: http://www.expasy.ch/sprot/ and http://www.ebi.ac.uk/swissprot/
SWISS-PROT是一个经过精心整理的蛋白质序列数据库，致力于提供高水平的注释（如蛋白质功能描述、结构域结构、翻译后修饰、变体等），冗余度降至最低，并与其他数据库高度整合。该数据库的最新进展包括格式和内容的改进、与其他数据库的交叉引用、新的文档文件以及对TrEMBL（SWISS-PROT的计算机注释补充数据库）的改进。TrEMBL由从EMBL核苷酸序列数据库中所有编码序列（CDS）翻译而来的类似SWISS-PROT格式的条目组成，但不包括已包含在SWISS-PROT中的CDS。我们还描述了人类蛋白质组计划（HPI），这是一个根据SWISS-PROT的质量标准注释所有已知人类序列的重大项目。可通过以下网址访问SWISS-PROT：http://www.expasy.ch/sprot/ 以及http://www.ebi.ac.uk/swissprot/
Zotero 插件