Zwieb C, Wower J
Department of Molecular Biology, The University of Texas Health Science Center at Tyler, 11937 US Highway 271, Tyler, TX 75708-3154, USA.
Nucleic Acids Res. 2000 Jan 1;28(1):169-70. doi: 10.1093/nar/28.1.169.
The tmRNA database (tmRDB) is maintained at the University of Texas Health Science Center at Tyler, Texas, and is accessible on the WWW at URL http://psyche.uthct.edu/dbs/tmRDB/tmRDB.++ +html. A tmRDB mirror site is located on the campus of Auburn University, Auburn, Alabama, reachable at the URL http://www.ag.auburn.edu/mirror/tmRDB/. Since April 1997, the tmRDB has provided sequences of tmRNA (previously called 10Sa RNA), a molecule present in most bacteria and some organelles. This release adds 17 new sequences for a total of 60 tmRNAs. Sequences and corresponding tmRNA-encoded tag peptides are tabulated in alphabetical and phylo-genetic order. The updated tmRNA alignment improves the secondary structures of known tmRNAs on the level of individual basepairs. tmRDB also provides an introduction to tmRNA function in trans-translation (with links to relevant literature), a limited number of tmRNA secondary structure diagrams, and numerous three-dimensional models generated interactively with the program ERNA-3D.
转运信使核糖核酸数据库(tmRDB)由位于得克萨斯州泰勒市的得克萨斯大学健康科学中心维护,可通过网址http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html在万维网上访问。tmRDB镜像站点位于阿拉巴马州奥本大学的校园内,网址为http://www.ag.auburn.edu/mirror/tmRDB/。自1997年4月以来,tmRDB一直提供转运信使核糖核酸(以前称为10Sa RNA)的序列,这种分子存在于大多数细菌和一些细胞器中。此次发布新增了17条新序列,使转运信使核糖核酸的总数达到60条。序列以及相应的由转运信使核糖核酸编码的标签肽按字母顺序和系统发育顺序制成表格。更新后的转运信使核糖核酸比对在单个碱基对水平上改善了已知转运信使核糖核酸的二级结构。tmRDB还介绍了转运信使核糖核酸在反式翻译中的功能(并提供相关文献的链接)、数量有限的转运信使核糖核酸二级结构图,以及通过ERNA - 3D程序交互式生成的众多三维模型。