转移信使核糖核酸网站。
The tmRNA website.
作者信息
Williams K P
机构信息
Department of Biology, Jordan Hall A411, Indiana University, Bloomington, IN 47405, USA.
出版信息
Nucleic Acids Res. 1999 Jan 1;27(1):165-6. doi: 10.1093/nar/27.1.165.
tmRNA (10Sa RNA) has a central role in trans -translation, in which a peptide tag encoded in tmRNA is added to the abnormally short protein product of a broken mRNA, as a signal for proteolysis of the entire tagged protein. The tmRNA website was established in 1997 as a resource for phylogenetic considerations of tmRNA structure and function. Since then, three partial tmRNA sequences have been completed, and sequences from 13 more species have been identified. Forty-six species from 10 bacterial phyla and chloroplasts are now represented in the database. Provisional sequence alignments and predicted proteolysis tag sequences are provided, as well as a literature review and a guide to searching for new tmRNA sequences. The tmRNA website is accessible via WWW at a new URL: http://sunflower.bio.indiana.edu/kwilliam/tmRNA /home.html
转运信使核糖核酸（10Sa RNA）在反式翻译中起着核心作用，在反式翻译过程中，转运信使核糖核酸编码的肽标签会添加到断裂信使核糖核酸异常短的蛋白质产物上，作为整个带标签蛋白质进行蛋白水解的信号。转运信使核糖核酸网站于1997年建立，作为对转运信使核糖核酸结构和功能进行系统发育研究的资源。从那时起，已完成了三个转运信使核糖核酸的部分序列，并且又鉴定出了来自另外13个物种的序列。数据库中现在有来自10个细菌门和叶绿体的46个物种。提供了临时序列比对和预测的蛋白水解标签序列，以及文献综述和搜索新转运信使核糖核酸序列的指南。可通过万维网在新的网址访问转运信使核糖核酸网站：http://sunflower.bio.indiana.edu/kwilliam/tmRNA /home.html
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