Song M G, Park K B, Lee E S
Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Dermatol Surg. 1999 Dec;25(12):970-3. doi: 10.1046/j.1524-4725.1999.99132.x.
Angiofibromas are a common presentation of tuberous sclerosis. They cause considerable cosmetic and hygienic morbidity for patients. Treatments of angiofibromas have included curettage, cryosurgery, chemical peel, dermabrasion, shave excision, and 13-cis retinoic acid. Results from these modalities in many cases were not satisfactory from a cosmetic standpoint. Copper vapor, argon, pulsed dye, and CO2 lasers have been used with success in isolated cases.
The purpose of this study was to evaluate the efficacy of CO2 laser resurfacing with flashscanner in the treatment of facial angiofibromas.
Two patients with angiofibromas on the face were treated with a CO2 laser with flashscanner. The cheek and nose were treated in one patient, and entire face was done in the other.
Both patients showed remarkable cosmetic improvements without scarring. Mild hyperpigmentation was found in both patients, which disappeared in 1 month with the application of topical agents. Facial erythema persisted about 2 months in both patients.
A CO2 laser equipped with flashscanner causes less residual thermal damage than conventional CO2 lasers and enables controlled depth vaporization for more precise and regular removal of angiofibromas. In whole-face resurfacing, more cosmetically acceptable results are possible because localized treatment leaves marginal prominences. Laser resurfacing is an effective alternative in the treatment of multiple protuberant angiofibromas even though we cannot permanently clear these lesions due to their nature.
血管纤维瘤是结节性硬化症的常见表现。它们给患者带来了相当大的美容和卫生方面的问题。血管纤维瘤的治疗方法包括刮除术、冷冻手术、化学剥脱术、磨皮术、剃除切除术和13 - 顺式维甲酸。从美容角度来看,这些方法在许多情况下的效果并不令人满意。铜蒸气激光、氩激光、脉冲染料激光和二氧化碳激光在个别病例中已成功应用。
本研究的目的是评估使用闪式扫描器的二氧化碳激光表面重建术治疗面部血管纤维瘤的疗效。
两名面部患有血管纤维瘤的患者接受了使用闪式扫描器的二氧化碳激光治疗。一名患者的脸颊和鼻子接受了治疗,另一名患者则对整个面部进行了治疗。
两名患者均显示出显著的美容改善且无瘢痕形成。两名患者均出现轻度色素沉着,使用外用药物后1个月内消失。两名患者面部红斑均持续约2个月。
配备闪式扫描器的二氧化碳激光比传统二氧化碳激光产生的残余热损伤更少,并且能够进行可控深度的汽化,以便更精确、规则地去除血管纤维瘤。在全脸表面重建中,由于局部治疗会留下边缘突出部分,因此可能会获得更美观的效果。激光表面重建术是治疗多发性突出性血管纤维瘤的一种有效替代方法,尽管由于其性质我们无法永久清除这些病变。